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Solvation-Guided Design of Fluorescent Probes for Discrimination of Amyloids
The deposition of insoluble protein aggregates in the brain is a hallmark of many neurodegenerative diseases. While their exact role in neurodegeneration remains unclear, the presence of these amyloid deposits often precedes clinical symptoms. As a result, recent progress in imaging methods that uti...
Autores principales: | Cao, Kevin J., Elbel, Kristyna M., Cifelli, Jessica L., Cirera, Jordi, Sigurdson, Christina J., Paesani, Francesco, Theodorakis, Emmanuel A., Yang, Jerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934448/ https://www.ncbi.nlm.nih.gov/pubmed/29725045 http://dx.doi.org/10.1038/s41598-018-25131-2 |
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