Arc 3′ UTR Splicing Leads to Dual and Antagonistic Effects in Fine-Tuning Arc Expression Upon BDNF Signaling

Activity-regulated cytoskeletal associated protein (Arc) is an immediate-early gene critically involved in synaptic plasticity and memory consolidation. Arc mRNA is rapidly induced by synaptic activation and a portion is locally translated in dendrites where it modulates synaptic strength. Being an...

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Detalles Bibliográficos
Autores principales: Paolantoni, Chiara, Ricciardi, Simona, De Paolis, Veronica, Okenwa, Chinenye, Catalanotto, Caterina, Ciotti, Maria T., Cattaneo, Antonino, Cogoni, Carlo, Giorgi, Corinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934489/
https://www.ncbi.nlm.nih.gov/pubmed/29755318
http://dx.doi.org/10.3389/fnmol.2018.00145

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