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Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast
The Rif1 protein negatively regulates telomeric TG repeat length in the budding yeast Saccharomyces cerevisiae, but how it prevents telomere over-extension is unknown. Rif1 was recently shown to control DNA replication by acting as a Protein Phosphatase 1 (PP1)-targeting subunit. Therefore, we inves...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934629/ https://www.ncbi.nlm.nih.gov/pubmed/29529242 http://dx.doi.org/10.1093/nar/gky132 |