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Quantifying the stability of oxidatively damaged DNA by single-molecule DNA stretching

One of the most common DNA lesions is created when reactive oxygen alters guanine. 8-oxo-guanine may bind in the anti-conformation with an opposing cytosine or in the syn-conformation with an opposing adenine paired by transversion, and both conformations may alter DNA stability. Here we use optical...

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Detalles Bibliográficos
Autores principales:	McCauley, Micah J, Furman, Leah, Dietrich, Catherine A, Rouzina, Ioulia, Núñez, Megan E, Williams, Mark C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934642/ https://www.ncbi.nlm.nih.gov/pubmed/29522114 http://dx.doi.org/10.1093/nar/gky148

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