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Unstructured 5′-tails act through ribosome standby to override inhibitory structure at ribosome binding sites
Initiation is the rate-limiting step in translation. It is well-known that stable structure at a ribosome binding site (RBS) impedes initiation. The ribosome standby model of de Smit and van Duin, based on studies of the MS2 phage coat cistron, proposed how high translation rates can be reconciled w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934652/ https://www.ncbi.nlm.nih.gov/pubmed/29420821 http://dx.doi.org/10.1093/nar/gky073 |