Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue

Emissive base analogs are powerful tools for probing nucleic acids at the molecular level. Herein we describe the development and thorough characterization of pentacyclic adenine (pA), a versatile base analog with exceptional fluorescence properties. When incorporated into DNA, pA pairs selectively...

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Detalles Bibliográficos
Autores principales: Bood, Mattias, Füchtbauer, Anders F., Wranne, Moa S., Ro, Jong Jin, Sarangamath, Sangamesh, El-Sagheer, Afaf H., Rupert, Déborah L. M., Fisher, Rachel S., Magennis, Steven W., Jones, Anita C., Höök, Fredrik, Brown, Tom, Kim, Byeang Hyean, Dahlén, Anders, Wilhelmsson, L. Marcus, Grøtli, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934695/
https://www.ncbi.nlm.nih.gov/pubmed/29780479
http://dx.doi.org/10.1039/c7sc05448c

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