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Aberrant microRNA-137 promoter methylation is associated with lymph node metastasis and poor clinical outcomes in non-small cell lung cancer

MicroRNA-137 (miR-137) functions as a tumor suppressor and is silenced by aberrant promoter methylation. Previous studies have demonstrated that miR-137 is downregulated in lung cancer. The purpose of the present study was to investigate miR-137 promoter methylation and to assess its prognostic valu...

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Detalles Bibliográficos
Autores principales: Min, Lingfeng, Wang, Fang, Hu, Suwei, Chen, Yong, Yang, Junjun, Liang, Sudong, Xu, Xingxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934732/
https://www.ncbi.nlm.nih.gov/pubmed/29740491
http://dx.doi.org/10.3892/ol.2018.8273