Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies

Recently, we studied glucose-nucleobase pairs, a binding motif found in aminoglycoside–RNA recognition. DNA duplexes with glucose as a nucleobase were able to hybridize and were selective for purines. They were less stable than natural DNA but still fit well on regular B-DNA. These results opened up...

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Detalles Bibliográficos
Autores principales: Vengut-Climent, Empar, Peñalver, Pablo, Lucas, Ricardo, Gómez-Pinto, Irene, Aviñó, Anna, Muro-Pastor, Alicia M., Galbis, Elsa, de Paz, M. Violante, Fonseca Guerra, Célia, Bickelhaupt, F. Matthias, Eritja, Ramón, González, Carlos, Morales, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934746/
https://www.ncbi.nlm.nih.gov/pubmed/29780486
http://dx.doi.org/10.1039/c7sc04850e

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