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Stress granules counteract senescence by sequestration of PAI‐1

Cellular senescence is a physiological response by which an organism halts the proliferation of potentially harmful and damaged cells. However, the accumulation of senescent cells over time can become deleterious leading to diseases and physiological decline. Our data reveal a novel interplay betwee...

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Detalles Bibliográficos
Autores principales: Omer, Amr, Patel, Devang, Lian, Xian Jin, Sadek, Jason, Di Marco, Sergio, Pause, Arnim, Gorospe, Myriam, Gallouzi, Imed Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934773/
https://www.ncbi.nlm.nih.gov/pubmed/29592859
http://dx.doi.org/10.15252/embr.201744722