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Vemurafenib in Chinese patients with BRAF(V600) mutation–positive unresectable or metastatic melanoma: an open-label, multicenter phase I study

BACKGROUND: Melanoma is a rare, deadly disease without effective treatment options in China. Vemurafenib is a selective inhibitor of oncogenic BRAF(V600) kinase approved in more than 90 countries, based on results obtained primarily in Caucasian patients. Limited data are available regarding the eff...

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Detalles Bibliográficos
Autores principales: Si, Lu, Zhang, Xiaoshi, Xu, Zhen, Jiang, Qiudi, Bu, Lilian, Wang, Xuan, Mao, Lili, Zhang, Weijiang, Richie, Nicole, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934791/
https://www.ncbi.nlm.nih.gov/pubmed/29724167
http://dx.doi.org/10.1186/s12885-018-4336-3

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