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Vemurafenib in Chinese patients with BRAF(V600) mutation–positive unresectable or metastatic melanoma: an open-label, multicenter phase I study
BACKGROUND: Melanoma is a rare, deadly disease without effective treatment options in China. Vemurafenib is a selective inhibitor of oncogenic BRAF(V600) kinase approved in more than 90 countries, based on results obtained primarily in Caucasian patients. Limited data are available regarding the eff...
Autores principales: | Si, Lu, Zhang, Xiaoshi, Xu, Zhen, Jiang, Qiudi, Bu, Lilian, Wang, Xuan, Mao, Lili, Zhang, Weijiang, Richie, Nicole, Guo, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934791/ https://www.ncbi.nlm.nih.gov/pubmed/29724167 http://dx.doi.org/10.1186/s12885-018-4336-3 |
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