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Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP

In pancreatic β-cells, insulin granule membranes are enriched in cholesterol and are both recycled and newly generated. Cholesterol’s role in supporting granule membrane formation and function is poorly understood. ATP binding cassette transporters ABCG1 and ABCA1 regulate intracellular cholesterol...

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Detalles Bibliográficos
Autores principales:	Hussain, Syed Saad, Harris, Megan T., Kreutzberger, Alex J. B., Inouye, Candice M., Doyle, Catherine A., Castle, Anna M., Arvan, Peter, Castle, J. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935073/ https://www.ncbi.nlm.nih.gov/pubmed/29540530 http://dx.doi.org/10.1091/mbc.E17-08-0519

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