Cargando…

Angiotensin II type 2 receptor agonist Compound 21 attenuates pulmonary inflammation in a model of acute lung injury

PURPOSE: Although the role of the angiotensin II type 2 (AT2) receptor in acute lung injury is not yet completely understood, a protective role of this receptor subtype has been suggested. We hypothesized that, in a rodent model of acute lung injury, stimulation of the AT2 receptor with the direct a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Menk, Mario, Graw, Jan Adriaan, von Haefen, Clarissa, Steinkraus, Hendrik, Lachmann, Burkhard, Spies, Claudia D, Schwaiberger, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935084/ https://www.ncbi.nlm.nih.gov/pubmed/29750051 http://dx.doi.org/10.2147/JIR.S160573

Ejemplares similares

Chronic Alcohol Consumption Inhibits Autophagy and Promotes Apoptosis in the Liver
por: Menk, Mario, et al.
Publicado: (2018)

Innate immunity recovers earlier than acquired immunity during severe postoperative immunosuppression
por: Lachmann, Gunnar, et al.
Publicado: (2018)

Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model
por: Lanzke, Nadine, et al.
Publicado: (2017)

In vivo application of Granulocyte-Macrophage Colony-stimulating Factor enhances postoperative qualitative monocytic function
por: Lachmann, Gunnar, et al.
Publicado: (2017)

Smoking, Gender, and Overweight Are Important Influencing Factors on Monocytic HLA-DR before and after Major Cancer Surgery
por: Lachmann, Gunnar, et al.
Publicado: (2017)

Chronic Alcohol Consumption Leads to a Tissue Specific Expression of Uncoupling Protein-2
por: Graw, Jan A., et al.
Publicado: (2015)

Preoperative hypoalbuminaemia in liver surgery: an observational study at a university medical centre
por: Kuhlmann, Anna Dorothea, et al.
Publicado: (2023)

Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats
por: Dai, Shu-Yan, et al.
Publicado: (2016)

Automatic protective ventilation using the ARDSNet protocol with the additional monitoring of electrical impedance tomography
por: Pomprapa, Anake, et al.
Publicado: (2014)

Influence of Granulocyte-Macrophage Colony-Stimulating Factor or Influenza Vaccination on HLA-DR, Infection and Delirium Days in Immunosuppressed Surgical Patients: Double Blind, Randomised Controlled Trial
por: Spies, Claudia, et al.
Publicado: (2015)

Dexmedetomidine Prevents Lipopolysaccharide-Induced MicroRNA Expression in the Adult Rat Brain
por: Paeschke, Nadine, et al.
Publicado: (2017)

The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury
por: Rathinasabapathy, Anandharajan, et al.
Publicado: (2018)

Comparison of a fully automatic ARDSNet protocol and a feedback-controlled open lung management concept
por: Pomprapa, A, et al.
Publicado: (2013)

Neuroprotective effects of dexmedetomidine against hyperoxia-induced injury in the developing rat brain
por: Endesfelder, Stefanie, et al.
Publicado: (2017)

Efficacy and safety of argatroban in patients with acute respiratory distress syndrome and extracorporeal lung support
por: Menk, Mario, et al.
Publicado: (2017)

In a secondary analysis from a randomised, double-blind placebo-controlled trial Dexmedetomidine blocks cholinergic dysregulation in delirium pathogenesis in patients with major surgery
por: Jacob, Yanite, et al.
Publicado: (2023)

Circadian rhythms in septic shock patients
por: Lachmann, Gunnar, et al.
Publicado: (2021)

Direct Angiotensin AT2 Receptor Stimulation Using a Novel AT2 Receptor Agonist, Compound 21, Evokes Neuroprotection in Conscious Hypertensive Rats
por: McCarthy, Claudia A., et al.
Publicado: (2014)

Abstract QS38: Effect of Compound 21, a Selective Angiotensin II Type 2 Receptor Agonist, in an Abdominal Adhesion Murine Model
por: Boudreau, Colton, et al.
Publicado: (2019)

Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model
por: Kalb, Alexander, et al.
Publicado: (2013)

Correction: Acetylcholinesterase Inhibitors Reduce Neuroinflammation and -Degeneration in the Cortex and Hippocampus of a Surgery Stress Rat Model
por: Kalb, Alexander, et al.
Publicado: (2013)

Neuroprotective Effect of Dexmedetomidine on Hyperoxia-Induced Toxicity in the Neonatal Rat Brain
por: Sifringer, Marco, et al.
Publicado: (2015)

The selective α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced inflammation and lung injury
por: Kox, M, et al.
Publicado: (2009)

The Effect of a Nonpeptide Angiotensin II Type 2 Receptor Agonist, Compound 21, on Aortic Aneurysm Growth in a Mouse Model of Marfan Syndrome
por: Verbrugghe, Peter, et al.
Publicado: (2018)

Effects of compound 21, a non-peptide angiotensin II type 2 receptor agonist, on general anesthesia-induced cerebral injury in neonatal rats
por: Yong, Jun, et al.
Publicado: (2018)

Closed-loop mechanical ventilation for lung injury: a novel physiological-feedback mode following the principles of the open lung concept
por: Schwaiberger, David, et al.
Publicado: (2017)

Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21
por: Laukkanen, Liina, et al.
Publicado: (2021)

Dexmedetomidine Restores Autophagic Flux, Modulates Associated microRNAs and the Cholinergic Anti-inflammatory Pathway upon LPS-Treatment in Rats
por: Kho, Widuri, et al.
Publicado: (2021)

Protective Effect of Dexmedetomidine against Hyperoxia-Damaged Cerebellar Neurodevelopment in the Juvenile Rat
por: Puls, Robert, et al.
Publicado: (2023)

Dexmedetomidine Protects Cerebellar Neurons against Hyperoxia-Induced Oxidative Stress and Apoptosis in the Juvenile Rat
por: Puls, Robert, et al.
Publicado: (2023)

Cardioprotective Effects of Dexmedetomidine in an Oxidative-Stress In Vitro Model of Neonatal Rat Cardiomyocytes
por: Borger, Moritz, et al.
Publicado: (2023)

Cannabinoid receptor agonist attenuates angiotensin II–induced enlargement and mitochondrial dysfunction in rat atrial cardiomyocytes
por: Altieri, Danielle I., et al.
Publicado: (2023)

Potential of cell-free hemoglobin and haptoglobin as prognostic markers in patients with ARDS and treatment with veno-venous ECMO
por: Bünger, Victoria, et al.
Publicado: (2023)

Hemolysis in patients with Extracorporeal Membrane Oxygenation therapy for severe Acute Respiratory Distress Syndrome - a systematic review of the literature
por: Materne, Lorenz A., et al.
Publicado: (2021)

Inhibition of Acetylcholinesterase Modulates NMDA Receptor Antagonist Mediated Alterations in the Developing Brain
por: Bendix, Ivo, et al.
Publicado: (2014)

The role of cell-free hemoglobin and haptoglobin in acute kidney injury in critically ill adults with ARDS and therapy with VV ECMO
por: Graw, Jan A., et al.
Publicado: (2022)

Serum neurofilament light chain in COVID-19 and the influence of renal function
por: Körtvelyessy, Peter, et al.
Publicado: (2023)

Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill patients (HEMICU): a prospective observational study protocol
por: Lachmann, Gunnar, et al.
Publicado: (2019)

The long-acting β(2)-adrenoceptor agonist olodaterol attenuates pulmonary inflammation
por: Wex, Eva, et al.
Publicado: (2015)

Effects of the Oral Angiotensin II Type 2 Receptor Agonist C21 in Sugen-Hypoxia Induced Pulmonary Hypertension in Rats
por: Tornling, Göran, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a6k005aphqh282b08ck3m3l4do