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Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence

High mobility group box 2 (HMGB2) is an abundant, chromatin-associated, non-histone protein involved in transcription, chromatin remodeling, and recombination. Recently, the HMGB2 gene was found to be significantly downregulated during senescence and shown to regulate the expression of senescent-ass...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Kyung, Kang, Mi Ae, Kim, Mi-Sook, Shin, Young-Joo, Chi, Sung-Gil, Jeong, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093/
https://www.ncbi.nlm.nih.gov/pubmed/29487276
http://dx.doi.org/10.14348/molcells.2018.2291