A Quantitative Chemotherapy Genetic Interaction Map Reveals Factors Associated with PARP Inhibitor Resistance

Chemotherapy is used to treat most cancer patients, yet our understanding of factors that dictate response and resistance to such drugs remains limited. We report the generation of a quantitative chemical-genetic interaction map in human mammary epithelial cells charting the impact of the knockdown...

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Detalles Bibliográficos
Autores principales: Hu, Hsien-Ming, Zhao, Xin, Kaushik, Swati, Robillard, Lilliane, Barthelet, Antoine, Lin, Kevin K., Shah, Khyati N., Simmons, Andy D., Raponi, Mitch, Harding, Thomas C., Bandyopadhyay, Sourav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935461/
https://www.ncbi.nlm.nih.gov/pubmed/29669295
http://dx.doi.org/10.1016/j.celrep.2018.03.093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935461/
https://www.ncbi.nlm.nih.gov/pubmed/29669295
http://dx.doi.org/10.1016/j.celrep.2018.03.093

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