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Preparation of Chitin-PLA laminated composite for implantable application

The present study explores the possibilities of using locally available inexpensive waste prawn shell derived chitin reinforced and bioabsorbable polylactic acid (PLA) laminated composites to develop new materials with excellent mechanical and thermal properties for implantable application such as i...

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Detalles Bibliográficos
Autores principales: Nasrin, Romana, Biswas, Shanta, Rashid, Taslim Ur, Afrin, Sanjida, Jahan, Rumana Akhter, Haque, Papia, Rahman, Mohammed Mizanur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935514/
https://www.ncbi.nlm.nih.gov/pubmed/29744430
http://dx.doi.org/10.1016/j.bioactmat.2017.09.003
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author Nasrin, Romana
Biswas, Shanta
Rashid, Taslim Ur
Afrin, Sanjida
Jahan, Rumana Akhter
Haque, Papia
Rahman, Mohammed Mizanur
author_facet Nasrin, Romana
Biswas, Shanta
Rashid, Taslim Ur
Afrin, Sanjida
Jahan, Rumana Akhter
Haque, Papia
Rahman, Mohammed Mizanur
author_sort Nasrin, Romana
collection PubMed
description The present study explores the possibilities of using locally available inexpensive waste prawn shell derived chitin reinforced and bioabsorbable polylactic acid (PLA) laminated composites to develop new materials with excellent mechanical and thermal properties for implantable application such as in bone or dental implant. Chitin at different concentration (1–20% of PLA) reinforced PLA films (CTP) were fabricated by solvent casting process and laminated chitin-PLA composites (LCTP) were prepared by laminating PLA film (obtained by hot press method) with CTP also by hot press method at 160 °C. The effect of variation of chitin concentration on the resulting laminated composite's behavior was investigated. The detailed physico-mechanical, surface morphology and thermal were assessed with different characterization technique such as FT-IR, XRD, SEM and TGA. The FTIR spectra showed the characteristic peaks for chitin and PLA in the composites. SEM images showed an excellent dispersion of chitin in the films and composites. Thermogravimetric analysis (TGA) showed that the complete degradation of chitin, PLA film, 5% chitin reinforced PLA film (CTP2) and LCTP are 98%, 95%, 87% and 98% respectively at temperature of 500 °C. The tensile strength of the LCTP was found 25.09 MPa which is significantly higher than pure PLA film (18.55 MPa) and CTP2 film (8.83 MPa). After lamination of pure PLA and CTP2 film, the composite (LCTP) yielded 0.265–1.061% water absorption from 30 min to 24 h immerse in water that is much lower than PLA and CTP. The increased mechanical properties of the laminated films with the increase of chitin content indicated good dispersion of chitin into PLA and strong interfacial actions between the polymer and chitin. The improvement of mechanical properties and the results of antimicrobial and cytotoxicity of the composites also evaluated and revealed the composite would be a suitable candidate for implant application in biomedical sector.
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spelling pubmed-59355142018-05-09 Preparation of Chitin-PLA laminated composite for implantable application Nasrin, Romana Biswas, Shanta Rashid, Taslim Ur Afrin, Sanjida Jahan, Rumana Akhter Haque, Papia Rahman, Mohammed Mizanur Bioact Mater Bioactive Composite The present study explores the possibilities of using locally available inexpensive waste prawn shell derived chitin reinforced and bioabsorbable polylactic acid (PLA) laminated composites to develop new materials with excellent mechanical and thermal properties for implantable application such as in bone or dental implant. Chitin at different concentration (1–20% of PLA) reinforced PLA films (CTP) were fabricated by solvent casting process and laminated chitin-PLA composites (LCTP) were prepared by laminating PLA film (obtained by hot press method) with CTP also by hot press method at 160 °C. The effect of variation of chitin concentration on the resulting laminated composite's behavior was investigated. The detailed physico-mechanical, surface morphology and thermal were assessed with different characterization technique such as FT-IR, XRD, SEM and TGA. The FTIR spectra showed the characteristic peaks for chitin and PLA in the composites. SEM images showed an excellent dispersion of chitin in the films and composites. Thermogravimetric analysis (TGA) showed that the complete degradation of chitin, PLA film, 5% chitin reinforced PLA film (CTP2) and LCTP are 98%, 95%, 87% and 98% respectively at temperature of 500 °C. The tensile strength of the LCTP was found 25.09 MPa which is significantly higher than pure PLA film (18.55 MPa) and CTP2 film (8.83 MPa). After lamination of pure PLA and CTP2 film, the composite (LCTP) yielded 0.265–1.061% water absorption from 30 min to 24 h immerse in water that is much lower than PLA and CTP. The increased mechanical properties of the laminated films with the increase of chitin content indicated good dispersion of chitin into PLA and strong interfacial actions between the polymer and chitin. The improvement of mechanical properties and the results of antimicrobial and cytotoxicity of the composites also evaluated and revealed the composite would be a suitable candidate for implant application in biomedical sector. KeAi Publishing 2017-10-02 /pmc/articles/PMC5935514/ /pubmed/29744430 http://dx.doi.org/10.1016/j.bioactmat.2017.09.003 Text en © 2017 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Bioactive Composite
Nasrin, Romana
Biswas, Shanta
Rashid, Taslim Ur
Afrin, Sanjida
Jahan, Rumana Akhter
Haque, Papia
Rahman, Mohammed Mizanur
Preparation of Chitin-PLA laminated composite for implantable application
title Preparation of Chitin-PLA laminated composite for implantable application
title_full Preparation of Chitin-PLA laminated composite for implantable application
title_fullStr Preparation of Chitin-PLA laminated composite for implantable application
title_full_unstemmed Preparation of Chitin-PLA laminated composite for implantable application
title_short Preparation of Chitin-PLA laminated composite for implantable application
title_sort preparation of chitin-pla laminated composite for implantable application
topic Bioactive Composite
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935514/
https://www.ncbi.nlm.nih.gov/pubmed/29744430
http://dx.doi.org/10.1016/j.bioactmat.2017.09.003
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