Infant cardiopulmonary bypass: CD73 kinetics, association with clinical outcomes, and influence on serum adenosine production capacity

BACKGROUND: Extracellular adenine nucleotides contribute to ischemia–reperfusion injury following infant cardiopulmonary bypass (CPB), whereas conversion to adenosine may be protective. Alkaline phosphatase (AP), a key enzyme responsible for this conversion, decreases after infant CPB. Indirect evid...

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Detalles Bibliográficos
Autores principales: Persson, Jessica N, Baird, Christine H, Tong, Suhong, Urban, Tracy T, Klawitter, Jelena, Wischmeyer, Paul E, Davidson, Jesse A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935543/
https://www.ncbi.nlm.nih.gov/pubmed/29278640
http://dx.doi.org/10.1038/pr.2017.325

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