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Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function

We have reported that recombinant biglycan (BGN) core protein accelerates bone formation in vivo by enhancing bone morphogenetic protein (BMP)-2 function. The purpose of the present study was to identify the specific domain (“effector”) within the BGN core protein that facilitates BMP-2 osteogenic f...

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Detalles Bibliográficos
Autores principales: Jongwattanapisan, Prapaporn, Terajima, Masahiko, Miguez, Patricia A., Querido, William, Nagaoka, Hideaki, Sumida, Noriko, Gurysh, Elizabeth Grace, Ainslie, Kristy M., Pleshko, Nancy, Perera, Lalith, Yamauchi, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935668/
https://www.ncbi.nlm.nih.gov/pubmed/29728612
http://dx.doi.org/10.1038/s41598-018-25279-x