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Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function
We have reported that recombinant biglycan (BGN) core protein accelerates bone formation in vivo by enhancing bone morphogenetic protein (BMP)-2 function. The purpose of the present study was to identify the specific domain (“effector”) within the BGN core protein that facilitates BMP-2 osteogenic f...
Autores principales: | Jongwattanapisan, Prapaporn, Terajima, Masahiko, Miguez, Patricia A., Querido, William, Nagaoka, Hideaki, Sumida, Noriko, Gurysh, Elizabeth Grace, Ainslie, Kristy M., Pleshko, Nancy, Perera, Lalith, Yamauchi, Mitsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935668/ https://www.ncbi.nlm.nih.gov/pubmed/29728612 http://dx.doi.org/10.1038/s41598-018-25279-x |
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