Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin—resistant Staphylococcus aureus

The emergence of Staphylococcus aureus strains resistant to ‘last resort’ antibiotics compels the development of new antimicrobials against this important human pathogen. We found that propyl 5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC) shows bacteriostatic activity against S. aur...

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Detalles Bibliográficos
Autores principales: Johnston, Tatiana, Van Tyne, Daria, Chen, Roy F., Fawzi, Nicolas L., Kwon, Bumsup, Kelso, Michael J., Gilmore, Michael S., Mylonakis, Eleftherios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935714/
https://www.ncbi.nlm.nih.gov/pubmed/29728636
http://dx.doi.org/10.1038/s41598-018-25571-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935714/
https://www.ncbi.nlm.nih.gov/pubmed/29728636
http://dx.doi.org/10.1038/s41598-018-25571-w

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