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Egr2-independent, Klf1-mediated induction of PD-L1 in CD4(+) T cells

Programmed death ligand 1 (PD-L1)-mediated induction of immune tolerance has been vigorously investigated in autoimmunity and anti-tumor immunity. However, details of the mechanism by which PD-L1 is induced in CD4(+) T cells are unknown. Here, we revealed the potential function of Klf1 and Egr2-medi...

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Detalles Bibliográficos
Autores principales:	Teruya, Shuzo, Okamura, Tomohisa, Komai, Toshihiko, Inoue, Mariko, Iwasaki, Yukiko, Sumitomo, Shuji, Shoda, Hirofumi, Yamamoto, Kazuhiko, Fujio, Keishi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935736/ https://www.ncbi.nlm.nih.gov/pubmed/29728568 http://dx.doi.org/10.1038/s41598-018-25302-1

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