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3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances

3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequis...

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Detalles Bibliográficos
Autores principales: Derakhshanfar, Soroosh, Mbeleck, Rene, Xu, Kaige, Zhang, Xingying, Zhong, Wen, Xing, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935777/
https://www.ncbi.nlm.nih.gov/pubmed/29744452
http://dx.doi.org/10.1016/j.bioactmat.2017.11.008
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author Derakhshanfar, Soroosh
Mbeleck, Rene
Xu, Kaige
Zhang, Xingying
Zhong, Wen
Xing, Malcolm
author_facet Derakhshanfar, Soroosh
Mbeleck, Rene
Xu, Kaige
Zhang, Xingying
Zhong, Wen
Xing, Malcolm
author_sort Derakhshanfar, Soroosh
collection PubMed
description 3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequisite toward advancing 3D printing applications in tissue engineering. Printability to improve fabrication process and cell encapsulation are two of the main factors to be considered in development of 3D bioprinting. Other important factors include but are not limited to printing fidelity, stability, crosslinking time, biocompatibility, cell encapsulation and proliferation, shear-thinning properties, and mechanical properties such as mechanical strength and elasticity. In this review, we recite recent promising advances in bioink development as well as bioprinting methods. Also, an effort has been made to include studies with diverse types of crosslinking methods such as photo, chemical and ultraviolet (UV). We also propose the challenges and future outlook of 3D bioprinting application in medical sciences and discuss the high performance bioinks.
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spelling pubmed-59357772018-05-09 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances Derakhshanfar, Soroosh Mbeleck, Rene Xu, Kaige Zhang, Xingying Zhong, Wen Xing, Malcolm Bioact Mater Article 3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible biomaterials for bioprinting exhibiting fast crosslinking properties is an essential prerequisite toward advancing 3D printing applications in tissue engineering. Printability to improve fabrication process and cell encapsulation are two of the main factors to be considered in development of 3D bioprinting. Other important factors include but are not limited to printing fidelity, stability, crosslinking time, biocompatibility, cell encapsulation and proliferation, shear-thinning properties, and mechanical properties such as mechanical strength and elasticity. In this review, we recite recent promising advances in bioink development as well as bioprinting methods. Also, an effort has been made to include studies with diverse types of crosslinking methods such as photo, chemical and ultraviolet (UV). We also propose the challenges and future outlook of 3D bioprinting application in medical sciences and discuss the high performance bioinks. KeAi Publishing 2018-02-20 /pmc/articles/PMC5935777/ /pubmed/29744452 http://dx.doi.org/10.1016/j.bioactmat.2017.11.008 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Derakhshanfar, Soroosh
Mbeleck, Rene
Xu, Kaige
Zhang, Xingying
Zhong, Wen
Xing, Malcolm
3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_full 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_fullStr 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_full_unstemmed 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_short 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances
title_sort 3d bioprinting for biomedical devices and tissue engineering: a review of recent trends and advances
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935777/
https://www.ncbi.nlm.nih.gov/pubmed/29744452
http://dx.doi.org/10.1016/j.bioactmat.2017.11.008
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