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Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells

Embryonic stem cells (ESCs) cultured in leukemia inhibitory factor (LIF) plus fetal bovine serum (FBS) exhibit heterogeneity in the expression of naive and primed transcription factors. This heterogeneity reflects the dynamic condition of ESCs and their versatility to promptly respond to signaling e...

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Detalles Bibliográficos
Autores principales:	Acampora, Dario, Di Giovannantonio, Luca Giovanni, Garofalo, Arcomaria, Nigro, Vincenzo, Omodei, Daniela, Lombardi, Alessia, Zhang, Jingchao, Chambers, Ian, Simeone, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935799/ https://www.ncbi.nlm.nih.gov/pubmed/29056334 http://dx.doi.org/10.1016/j.stemcr.2017.09.019

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