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Heart rate modulation in stable coronary artery disease without clinical heart failure: What we have already learned from SIGNIFY?

An elevated heart rate is a marker of cardiovascular risk in patients with stable coronary artery disease. Ivabradine selectively inhibits the “f” current in the sinus node and reduces heart rate without any modifications of blood pressure, myocardial contractility and arteriolar resistance. However...

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Detalles Bibliográficos
Autores principales: Perna, Gian Piero, Vagnarelli, Fabio, Volterrani, Maurizio, Battistoni, Ilaria, Rapezzi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935893/
https://www.ncbi.nlm.nih.gov/pubmed/29736470
http://dx.doi.org/10.1016/j.conctc.2016.06.003