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IL-33/ST2 plays a critical role in endothelial cell activation and microglia-mediated neuroinflammation modulation
BACKGROUND: Interleukin-33 (IL-33) is increasingly being recognized as a key immunomodulatory cytokine in many neurological diseases. METHODS: In the present study, wild-type (WT) and IL-33(−/−) mice received intracerebroventricular (i.c.v.) injection of lipopolysaccharide (LPS) to induce neuroinfla...
Autores principales: | Cao, Kelei, Liao, Xiang, Lu, Jiahui, Yao, Shu, Wu, Fengjiao, Zhu, Xingxing, Shi, Dongyan, Wen, Shuang, Liu, Lixin, Zhou, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935936/ https://www.ncbi.nlm.nih.gov/pubmed/29728120 http://dx.doi.org/10.1186/s12974-018-1169-6 |
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