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From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel

BACKGROUND: ATP-sensitive inward rectifier potassium channels (Kir), are a potassium channel family involved in many physiological processes. K(ATP) dysfunctions are observed in several diseases such as hypoglycaemia, hyperinsulinemia, Prinzmetal angina–like symptoms, cardiovascular diseases. METHOD...

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Detalles Bibliográficos
Autores principales:	Trezza, Alfonso, Cicaloni, Vittoria, Porciatti, Piera, Langella, Andrea, Fusi, Fabio, Saponara, Simona, Spiga, Ottavia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2018
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936070/ https://www.ncbi.nlm.nih.gov/pubmed/29736333 http://dx.doi.org/10.7717/peerj.4680

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