Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis

For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene...

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Detalles Bibliográficos
Autores principales: Liu, Xuhui, Luo, Zong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2005
Materias:
Directions in Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936499/
https://www.ncbi.nlm.nih.gov/pubmed/15674443
http://dx.doi.org/10.1100/tsw.2005.6
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author Liu, Xuhui
Luo, Zong-Ping
author_facet Liu, Xuhui
Luo, Zong-Ping
author_sort Liu, Xuhui
collection PubMed
description For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts.
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spelling pubmed-59364992018-06-03 Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis Liu, Xuhui Luo, Zong-Ping ScientificWorldJournal Directions in Science For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts. TheScientificWorldJOURNAL 2005-01-14 /pmc/articles/PMC5936499/ /pubmed/15674443 http://dx.doi.org/10.1100/tsw.2005.6 Text en Copyright © 2005 Xuhui Liu and Zong-Ping Luo. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Directions in Science
Liu, Xuhui
Luo, Zong-Ping
Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_full Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_fullStr Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_full_unstemmed Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_short Combined Effects of Estrogen and Mechanical Loading on Anterior Cruciate Ligament Fibroblast Biosynthesis
title_sort combined effects of estrogen and mechanical loading on anterior cruciate ligament fibroblast biosynthesis
topic Directions in Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936499/
https://www.ncbi.nlm.nih.gov/pubmed/15674443
http://dx.doi.org/10.1100/tsw.2005.6
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AT luozongping combinedeffectsofestrogenandmechanicalloadingonanteriorcruciateligamentfibroblastbiosynthesis

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