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Lysosome-dependent cell death and deregulated autophagy induced by amine-modified polystyrene nanoparticles

Nanoparticles (NPs) typically accumulate in lysosomes. However, their impact on lysosomal function, as well as autophagy, a lysosomal degradative pathway, is still not well known. We have previously reported in the 1321N1 cell line that amine-modified polystyrene (NH(2)-PS) NPs induce apoptosis thro...

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Detalles Bibliográficos
Autores principales: Wang, Fengjuan, Salvati, Anna, Boya, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936715/
https://www.ncbi.nlm.nih.gov/pubmed/29643148
http://dx.doi.org/10.1098/rsob.170271

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