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Selective Modulation of TNF–TNFRs Signaling: Insights for Multiple Sclerosis Treatment

Autoimmunity develops when self-tolerance mechanisms are failing to protect healthy tissue. A sustained reaction to self is generated, which includes the generation of effector cells and molecules that destroy tissues. A way to restore this intrinsic tolerance is through immune modulation that aims...

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Detalles Bibliográficos
Autores principales: Pegoretti, Valentina, Baron, Wia, Laman, Jon D., Eisel, Ulrich L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936749/
https://www.ncbi.nlm.nih.gov/pubmed/29760711
http://dx.doi.org/10.3389/fimmu.2018.00925

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