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Selective Modulation of TNF–TNFRs Signaling: Insights for Multiple Sclerosis Treatment
Autoimmunity develops when self-tolerance mechanisms are failing to protect healthy tissue. A sustained reaction to self is generated, which includes the generation of effector cells and molecules that destroy tissues. A way to restore this intrinsic tolerance is through immune modulation that aims...
Autores principales: | Pegoretti, Valentina, Baron, Wia, Laman, Jon D., Eisel, Ulrich L. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936749/ https://www.ncbi.nlm.nih.gov/pubmed/29760711 http://dx.doi.org/10.3389/fimmu.2018.00925 |
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