Cargando…

High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis

BACKGROUND: The prevention and correction of vitamin D deficiency requires a precise depiction of the current situation and identification of risk factors in each region. The present study attempted to determine these entities using a systematic review and meta-analysis in Iran. METHODS: Articles pu...

Descripción completa

Detalles Bibliográficos
Autores principales: Tabrizi, Reza, Moosazadeh, Mahmood, Akbari, Maryam, Dabbaghmanesh, Mohammad Hossein, Mohamadkhani, Minoo, Asemi, Zatollah, Heydari, Seyed Taghi, Akbari, Mojtaba, Lankarani, Kamran B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Journal of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936844/
https://www.ncbi.nlm.nih.gov/pubmed/29749981
_version_ 1783320523208392704
author Tabrizi, Reza
Moosazadeh, Mahmood
Akbari, Maryam
Dabbaghmanesh, Mohammad Hossein
Mohamadkhani, Minoo
Asemi, Zatollah
Heydari, Seyed Taghi
Akbari, Mojtaba
Lankarani, Kamran B
author_facet Tabrizi, Reza
Moosazadeh, Mahmood
Akbari, Maryam
Dabbaghmanesh, Mohammad Hossein
Mohamadkhani, Minoo
Asemi, Zatollah
Heydari, Seyed Taghi
Akbari, Mojtaba
Lankarani, Kamran B
author_sort Tabrizi, Reza
collection PubMed
description BACKGROUND: The prevention and correction of vitamin D deficiency requires a precise depiction of the current situation and identification of risk factors in each region. The present study attempted to determine these entities using a systematic review and meta-analysis in Iran. METHODS: Articles published online in Persian and English between 2000 and November 1, 2016, were reviewed. This was carried out using national databases such as SID, IranMedex, Magiran, and IranDoc and international databases such as PubMed, Google Scholar, and Scopus. The heterogeneity index among the studies was determined using the Cochran (Q) and I(2) test. Based on the heterogeneity results, the random-effect model was applied to estimate the prevalence of vitamin D deficiency. In addition, meta-regression analysis was used to determine heterogeneity-suspected factors, and the Egger test was applied to identify publication bias. RESULTS: The meta-analysis of 48 studies identified 18531 individuals with vitamin D deficiency. According to the random-effect model, the prevalence of vitamin D deficiency among male, female, and pregnant women was estimated to be 45.64% (95% CI: 29.63 to 61.65), 61.90% (95% CI: 48.85 to 74.96), and 60.45% (95% CI: 23.73 to 97.16), respectively. The results of the meta-regression analysis indicated that the prevalence of vitamin D deficiency was significantly different in various geographical regions (β=4.4; P=0.023). CONCLUSION: The results obtained showed a significant prevalence of vitamin D deficiency among the Iranian population, a condition to be addressed by appropriate planning.
format Online
Article
Text
id pubmed-5936844
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Iranian Journal of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-59368442018-05-10 High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis Tabrizi, Reza Moosazadeh, Mahmood Akbari, Maryam Dabbaghmanesh, Mohammad Hossein Mohamadkhani, Minoo Asemi, Zatollah Heydari, Seyed Taghi Akbari, Mojtaba Lankarani, Kamran B Iran J Med Sci Review Article BACKGROUND: The prevention and correction of vitamin D deficiency requires a precise depiction of the current situation and identification of risk factors in each region. The present study attempted to determine these entities using a systematic review and meta-analysis in Iran. METHODS: Articles published online in Persian and English between 2000 and November 1, 2016, were reviewed. This was carried out using national databases such as SID, IranMedex, Magiran, and IranDoc and international databases such as PubMed, Google Scholar, and Scopus. The heterogeneity index among the studies was determined using the Cochran (Q) and I(2) test. Based on the heterogeneity results, the random-effect model was applied to estimate the prevalence of vitamin D deficiency. In addition, meta-regression analysis was used to determine heterogeneity-suspected factors, and the Egger test was applied to identify publication bias. RESULTS: The meta-analysis of 48 studies identified 18531 individuals with vitamin D deficiency. According to the random-effect model, the prevalence of vitamin D deficiency among male, female, and pregnant women was estimated to be 45.64% (95% CI: 29.63 to 61.65), 61.90% (95% CI: 48.85 to 74.96), and 60.45% (95% CI: 23.73 to 97.16), respectively. The results of the meta-regression analysis indicated that the prevalence of vitamin D deficiency was significantly different in various geographical regions (β=4.4; P=0.023). CONCLUSION: The results obtained showed a significant prevalence of vitamin D deficiency among the Iranian population, a condition to be addressed by appropriate planning. Iranian Journal of Medical Sciences 2018-03 /pmc/articles/PMC5936844/ /pubmed/29749981 Text en Copyright: © Iranian Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tabrizi, Reza
Moosazadeh, Mahmood
Akbari, Maryam
Dabbaghmanesh, Mohammad Hossein
Mohamadkhani, Minoo
Asemi, Zatollah
Heydari, Seyed Taghi
Akbari, Mojtaba
Lankarani, Kamran B
High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis
title High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis
title_full High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis
title_fullStr High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis
title_full_unstemmed High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis
title_short High Prevalence of Vitamin D Deficiency among Iranian Population: A Systematic Review and Meta-Analysis
title_sort high prevalence of vitamin d deficiency among iranian population: a systematic review and meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936844/
https://www.ncbi.nlm.nih.gov/pubmed/29749981
work_keys_str_mv AT tabrizireza highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT moosazadehmahmood highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT akbarimaryam highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT dabbaghmaneshmohammadhossein highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT mohamadkhaniminoo highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT asemizatollah highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT heydariseyedtaghi highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT akbarimojtaba highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis
AT lankaranikamranb highprevalenceofvitaminddeficiencyamongiranianpopulationasystematicreviewandmetaanalysis