High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)

There are three key medicinal components (phellodendrine, berberine and palmatine) in the extracts of Phellodendron bark, as one of the fundamental herbs of traditional Chinese medicine. Different extraction methods and solvent combinations were investigated to obtain the optimal technologies for hi...

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Autores principales: Xu, Keqin, He, Gongxiu, Qin, Jieming, Cheng, Xuexiang, He, Hanjie, Zhang, Dangquan, Peng, Wanxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936877/
https://www.ncbi.nlm.nih.gov/pubmed/29740248
http://dx.doi.org/10.1016/j.sjbs.2017.10.008
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author Xu, Keqin
He, Gongxiu
Qin, Jieming
Cheng, Xuexiang
He, Hanjie
Zhang, Dangquan
Peng, Wanxi
author_facet Xu, Keqin
He, Gongxiu
Qin, Jieming
Cheng, Xuexiang
He, Hanjie
Zhang, Dangquan
Peng, Wanxi
author_sort Xu, Keqin
collection PubMed
description There are three key medicinal components (phellodendrine, berberine and palmatine) in the extracts of Phellodendron bark, as one of the fundamental herbs of traditional Chinese medicine. Different extraction methods and solvent combinations were investigated to obtain the optimal technologies for high-efficient extraction of these medicinal components. Results: The results showed that combined solvents have higher extracting effect of phellodendrine, berberine and palmatine than single solvent, and the effect of ultrasonic extraction is distinctly better than those of distillation and soxhlet extraction. Conclusion: The hydrochloric acid/methanol-ultrasonic extraction has the best effect for three medicinal components of fresh Phellodendron bark, providing an extraction yield of 103.12 mg/g berberine, 24.41 mg/g phellodendrine, 1.25 mg/g palmatine.
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spelling pubmed-59368772018-05-08 High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri) Xu, Keqin He, Gongxiu Qin, Jieming Cheng, Xuexiang He, Hanjie Zhang, Dangquan Peng, Wanxi Saudi J Biol Sci Article There are three key medicinal components (phellodendrine, berberine and palmatine) in the extracts of Phellodendron bark, as one of the fundamental herbs of traditional Chinese medicine. Different extraction methods and solvent combinations were investigated to obtain the optimal technologies for high-efficient extraction of these medicinal components. Results: The results showed that combined solvents have higher extracting effect of phellodendrine, berberine and palmatine than single solvent, and the effect of ultrasonic extraction is distinctly better than those of distillation and soxhlet extraction. Conclusion: The hydrochloric acid/methanol-ultrasonic extraction has the best effect for three medicinal components of fresh Phellodendron bark, providing an extraction yield of 103.12 mg/g berberine, 24.41 mg/g phellodendrine, 1.25 mg/g palmatine. Elsevier 2018-05 2017-10-05 /pmc/articles/PMC5936877/ /pubmed/29740248 http://dx.doi.org/10.1016/j.sjbs.2017.10.008 Text en © 2016 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Xu, Keqin
He, Gongxiu
Qin, Jieming
Cheng, Xuexiang
He, Hanjie
Zhang, Dangquan
Peng, Wanxi
High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)
title High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)
title_full High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)
title_fullStr High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)
title_full_unstemmed High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)
title_short High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)
title_sort high-efficient extraction of principal medicinal components from fresh phellodendron bark (cortex phellodendri)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936877/
https://www.ncbi.nlm.nih.gov/pubmed/29740248
http://dx.doi.org/10.1016/j.sjbs.2017.10.008
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