A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone

Bolinaquinone is a natural product that is a structurally complex, cytotoxic sesquiterpene quinone. A scaffold simplification and focused library approach using a microwave-assisted Suzuki coupling gave 32 bolinaquinone analogues with good-to-excellent cytotoxicity profiles. Mono-arylbenzoquinones,...

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Detalles Bibliográficos
Autores principales: Ghods, Azadeh, Gilbert, Jayne, Baker, Jennifer R., Russell, Cecilia C., Sakoff, Jennette A., McCluskey, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936891/
https://www.ncbi.nlm.nih.gov/pubmed/29765626
http://dx.doi.org/10.1098/rsos.171189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936891/
https://www.ncbi.nlm.nih.gov/pubmed/29765626
http://dx.doi.org/10.1098/rsos.171189

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