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DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex

DGCR8 and DROSHA are the minimal functional core of the Microprocessor complex essential for biogenesis of canonical microRNAs and for the processing of other RNAs. Conditional deletion of Dgcr8 and Drosha in the murine telencephalon indicated that these proteins exert crucial functions in corticoge...

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Detalles Bibliográficos
Autores principales: Hoffmann, Nadin, Weise, Stefan C., Marinaro, Federica, Vogel, Tanja, De Pietri Tonelli, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936999/
https://www.ncbi.nlm.nih.gov/pubmed/29760646
http://dx.doi.org/10.3389/fnins.2018.00281

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