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Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C
BACKGROUND: Changes in metabolic pathway preferences are key events in the reprogramming process of somatic cells to induced pluripotent stem cells (iPSCs). The optimization of metabolic conditions can enhance reprogramming; however, the detailed underlying mechanisms are largely unclear. By compari...
Autores principales: | Lin, Zhaoyu, Liu, Fei, Shi, Peiliang, Song, Anying, Huang, Zan, Zou, Dayuan, Chen, Qin, Li, Jianxin, Gao, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937047/ https://www.ncbi.nlm.nih.gov/pubmed/29482657 http://dx.doi.org/10.1186/s13287-018-0792-6 |
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