Preclinical Study of Ibuprofen Loaded Transnasal Mucoadhesive Microemulsion for Neuroprotective Effect in MPTP Mice Model

Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), showed very promising neuroprotection action, but it suffers from high first pass metabolism and limited ability to cross blood brain barrier. Severe gastric toxicity following oral administration further limits its utility. Hence, the aim o...

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Detalles Bibliográficos
Autores principales: Mandal, Surjyanarayan, Mandal, Snigdha Das, Chuttani, Krishna, Sawant, Krutika K, Subudhi, Bharat Bhushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937075/
https://www.ncbi.nlm.nih.gov/pubmed/29755536

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