Prevention of Infection with Mycobacterium tuberculosis by H4:IC31® Vaccination or BCG Revaccination in Adolescents

BACKGROUND: Recent Mycobacterium tuberculosis (M.tb) infection predisposes to tuberculosis disease, the leading global infectious disease killer. We tested safety andefficacy of H4:IC31® vaccination or Bacille Calmette-Guerin (BCG) revaccination for prevention of M.tb infection. METHODS: QuantiFERON...

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Detalles Bibliográficos
Autores principales: Nemes, Elisa, Geldenhuys, Hennie, Rozot, Virginie, Tucker Rutkowski, Kathryn, Ratangee, Frances, Bilek, Nicole, Mabwe, Simbarashe, Makhethe, Lebohang, Erasmus, Mzwandile, Toefy, Asma, Mulenga, Humphrey, Hanekom, Willem A., Self, Steven G., Bekker, Linda-Gail, Ryall, Robert, Gurunathan, Sanjay, DiazGranados, Carlos A., Andersen, Peter, Kromann, Ingrid, Evans, Thomas, Ellis, Ruth D., Landry, Bernard, Hokey, David A., Hopkins, Robert, Ginsberg, Ann M., Scriba, Thomas J., Hatherill, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937161/
https://www.ncbi.nlm.nih.gov/pubmed/29996082
http://dx.doi.org/10.1056/NEJMoa1714021

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