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Early morphea simulating patch-stage mycosis fungoides in two cases
Morphea is a skin disorder characterized by thickening of dermis and subcutaneous tissues and loss of adnexal structures. In the early inflammatory stage of morphea, diagnostic histological findings are absent and this may lead to confusion with other inflammatory dermatoses such as mycosis fungoide...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937215/ https://www.ncbi.nlm.nih.gov/pubmed/29760873 http://dx.doi.org/10.4081/dr.2018.7477 |
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author | Basir, Hamid R. Ghasemi Alirezaei, Pedram Rezanejad, Aliasghar Daneshyar, Sajjad |
author_facet | Basir, Hamid R. Ghasemi Alirezaei, Pedram Rezanejad, Aliasghar Daneshyar, Sajjad |
author_sort | Basir, Hamid R. Ghasemi |
collection | PubMed |
description | Morphea is a skin disorder characterized by thickening of dermis and subcutaneous tissues and loss of adnexal structures. In the early inflammatory stage of morphea, diagnostic histological findings are absent and this may lead to confusion with other inflammatory dermatoses such as mycosis fungoides (MF). We report two cases of early stage morphea mimicking patchstage of MF. Histopathologic examination of biopsies obtained early in the disease course revealed lymphocytic epidermotropism arranged in small pautrier-like collections as well as linear arrangements in dermal- epidermal junction. Additional biopsies were performed which revealed replacement of subcutaneous fat with closely packed thick collagen bundles under eccrine glands. This report points toward the fact that early stage morphea can simulate MF. Therefore additional evaluation is sometimes required for definite diagnosis. |
format | Online Article Text |
id | pubmed-5937215 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-59372152018-05-14 Early morphea simulating patch-stage mycosis fungoides in two cases Basir, Hamid R. Ghasemi Alirezaei, Pedram Rezanejad, Aliasghar Daneshyar, Sajjad Dermatol Reports Case Report Morphea is a skin disorder characterized by thickening of dermis and subcutaneous tissues and loss of adnexal structures. In the early inflammatory stage of morphea, diagnostic histological findings are absent and this may lead to confusion with other inflammatory dermatoses such as mycosis fungoides (MF). We report two cases of early stage morphea mimicking patchstage of MF. Histopathologic examination of biopsies obtained early in the disease course revealed lymphocytic epidermotropism arranged in small pautrier-like collections as well as linear arrangements in dermal- epidermal junction. Additional biopsies were performed which revealed replacement of subcutaneous fat with closely packed thick collagen bundles under eccrine glands. This report points toward the fact that early stage morphea can simulate MF. Therefore additional evaluation is sometimes required for definite diagnosis. PAGEPress Publications, Pavia, Italy 2018-04-23 /pmc/articles/PMC5937215/ /pubmed/29760873 http://dx.doi.org/10.4081/dr.2018.7477 Text en ©Copyright H.R. Ghasemi Basir et al., 2018 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Basir, Hamid R. Ghasemi Alirezaei, Pedram Rezanejad, Aliasghar Daneshyar, Sajjad Early morphea simulating patch-stage mycosis fungoides in two cases |
title | Early morphea simulating patch-stage mycosis fungoides in two cases |
title_full | Early morphea simulating patch-stage mycosis fungoides in two cases |
title_fullStr | Early morphea simulating patch-stage mycosis fungoides in two cases |
title_full_unstemmed | Early morphea simulating patch-stage mycosis fungoides in two cases |
title_short | Early morphea simulating patch-stage mycosis fungoides in two cases |
title_sort | early morphea simulating patch-stage mycosis fungoides in two cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937215/ https://www.ncbi.nlm.nih.gov/pubmed/29760873 http://dx.doi.org/10.4081/dr.2018.7477 |
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