Comparison of the effects of deferasirox, deferoxamine, and combination of deferasirox and deferoxamine on an aplastic anemia mouse model complicated with iron overload

BACKGROUND AND AIM: Iron overload is commonly observed during the course of aplastic anemia (AA), which is believed to aggravate hematopoiesis, cause multiple organ dysfunction, lead to disease progression, and impair quality of life. Deferasirox (DFX) and deferoxamine (DFO) are among the most commo...

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Detalles Bibliográficos
Autores principales: Wu, Dijiong, Wen, Xiaowen, Liu, Wenbin, Hu, Huijin, Ye, Baodong, Zhou, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937503/
https://www.ncbi.nlm.nih.gov/pubmed/29760547
http://dx.doi.org/10.2147/DDDT.S161086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937503/
https://www.ncbi.nlm.nih.gov/pubmed/29760547
http://dx.doi.org/10.2147/DDDT.S161086

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