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Diethylnitrosamine Increases Proliferation in Early Stages of Hepatic Carcinogenesis in Insulin-Treated Type 1 Diabetic Mice

Diethylnitrosamine (DEN) induces hepatocarcinogenesis, increasing mitotic hepatocytes and leading to chronic inflammation. In addition, type 1 diabetes mellitus (T1DM) is also characterized by a proinflammatory state and by requiring insulin exogenous treatment. Given the association of diabetes, in...

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Detalles Bibliográficos
Autores principales: Arboatti, A. S., Lambertucci, F., Sedlmeier, M. G., Pisani, G., Monti, J., Álvarez, M. de L., Francés, D. E. A., Ronco, M. T., Carnovale, C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937583/
https://www.ncbi.nlm.nih.gov/pubmed/29850590
http://dx.doi.org/10.1155/2018/9472939