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TNF-α inhibits SCF, ghrelin, and substance P expressions through the NF-κB pathway activation in interstitial cells of Cajal

Ulcerative colitis is a chronic inflammatory disease of the colon where intestinal motility is disturbed. Interstitial cells of Cajal (ICC) are required to maintain normal intestinal motility. In the present study, we assessed the effect of tumor necrosis factor-alpha (TNF-α) on viability and apopto...

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Detalles Bibliográficos
Autores principales: Ren, Keyu, Yong, Chunming, Yuan, Hao, Cao, Bin, Zhao, Kun, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937728/
https://www.ncbi.nlm.nih.gov/pubmed/29694505
http://dx.doi.org/10.1590/1414-431X20187065