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Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes
The microbiome influences adaptive immunity and molecular mimicry influences T cell reactivity. Here, we evaluated whether the sequence similarity of various antigens to the microbiota dampens or increases immunogenicity of T cell epitopes. Sets of epitopes and control sequences derived from 38 anti...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937769/ https://www.ncbi.nlm.nih.gov/pubmed/29734356 http://dx.doi.org/10.1371/journal.pone.0196551 |