Non-canonical role of the SNARE protein Ykt6 in autophagosome-lysosome fusion

The autophagosomal SNARE Syntaxin17 (Syx17) forms a complex with Snap29 and Vamp7/8 to promote autophagosome-lysosome fusion via multiple interactions with the tethering complex HOPS. Here we demonstrate that, unexpectedly, one more SNARE (Ykt6) is also required for autophagosome clearance in Drosop...

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Detalles Bibliográficos
Autores principales: Takáts, Szabolcs, Glatz, Gábor, Szenci, Győző, Boda, Attila, Horváth, Gábor V., Hegedűs, Krisztina, Kovács, Attila L., Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937789/
https://www.ncbi.nlm.nih.gov/pubmed/29694367
http://dx.doi.org/10.1371/journal.pgen.1007359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937789/
https://www.ncbi.nlm.nih.gov/pubmed/29694367
http://dx.doi.org/10.1371/journal.pgen.1007359

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