Pathogen detection in the CRISPR–Cas era

CRISPR–Cas systems have provided revolutionary tools for genome editing. The discovery of Cas proteins with alternative activities has now enabled sensitive and robust tools for detecting nucleic acids. Recent reports harnessing these new CRISPR–Cas technologies display their potential for providing...

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Detalles Bibliográficos
Autor principal: Sashital, Dipali G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937823/
https://www.ncbi.nlm.nih.gov/pubmed/29690921
http://dx.doi.org/10.1186/s13073-018-0543-4
Descripción
Sumario:CRISPR–Cas systems have provided revolutionary tools for genome editing. The discovery of Cas proteins with alternative activities has now enabled sensitive and robust tools for detecting nucleic acids. Recent reports harnessing these new CRISPR–Cas technologies display their potential for providing low-cost and practical diagnostic tools for pathogen and disease detection.

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