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Theoretical model and characteristics of mitochondrial thermogenesis
Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation. The model settles the long-standing question of the ability to increase ce...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937889/ https://www.ncbi.nlm.nih.gov/pubmed/29756006 http://dx.doi.org/10.1007/s41048-018-0054-2 |
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author | Kang, Jian-Sheng |
author_facet | Kang, Jian-Sheng |
author_sort | Kang, Jian-Sheng |
collection | PubMed |
description | Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation. The model settles the long-standing question of the ability to increase cellular temperature by endogenous thermogenesis and explains the thermogenic characteristics of brown adipocytes. The model and calculations also suggest that the number of free available protons is the major limiting factor for endogenous thermogenesis and its speed. |
format | Online Article Text |
id | pubmed-5937889 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-59378892018-05-11 Theoretical model and characteristics of mitochondrial thermogenesis Kang, Jian-Sheng Biophys Rep Opinion Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation. The model settles the long-standing question of the ability to increase cellular temperature by endogenous thermogenesis and explains the thermogenic characteristics of brown adipocytes. The model and calculations also suggest that the number of free available protons is the major limiting factor for endogenous thermogenesis and its speed. Springer Berlin Heidelberg 2018-04-19 2018 /pmc/articles/PMC5937889/ /pubmed/29756006 http://dx.doi.org/10.1007/s41048-018-0054-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Opinion Kang, Jian-Sheng Theoretical model and characteristics of mitochondrial thermogenesis |
title | Theoretical model and characteristics of mitochondrial thermogenesis |
title_full | Theoretical model and characteristics of mitochondrial thermogenesis |
title_fullStr | Theoretical model and characteristics of mitochondrial thermogenesis |
title_full_unstemmed | Theoretical model and characteristics of mitochondrial thermogenesis |
title_short | Theoretical model and characteristics of mitochondrial thermogenesis |
title_sort | theoretical model and characteristics of mitochondrial thermogenesis |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937889/ https://www.ncbi.nlm.nih.gov/pubmed/29756006 http://dx.doi.org/10.1007/s41048-018-0054-2 |
work_keys_str_mv | AT kangjiansheng theoreticalmodelandcharacteristicsofmitochondrialthermogenesis |