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Theoretical model and characteristics of mitochondrial thermogenesis

Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation. The model settles the long-standing question of the ability to increase ce...

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Detalles Bibliográficos
Autor principal: Kang, Jian-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937889/
https://www.ncbi.nlm.nih.gov/pubmed/29756006
http://dx.doi.org/10.1007/s41048-018-0054-2
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author Kang, Jian-Sheng
author_facet Kang, Jian-Sheng
author_sort Kang, Jian-Sheng
collection PubMed
description Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation. The model settles the long-standing question of the ability to increase cellular temperature by endogenous thermogenesis and explains the thermogenic characteristics of brown adipocytes. The model and calculations also suggest that the number of free available protons is the major limiting factor for endogenous thermogenesis and its speed.
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spelling pubmed-59378892018-05-11 Theoretical model and characteristics of mitochondrial thermogenesis Kang, Jian-Sheng Biophys Rep Opinion Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation. The model settles the long-standing question of the ability to increase cellular temperature by endogenous thermogenesis and explains the thermogenic characteristics of brown adipocytes. The model and calculations also suggest that the number of free available protons is the major limiting factor for endogenous thermogenesis and its speed. Springer Berlin Heidelberg 2018-04-19 2018 /pmc/articles/PMC5937889/ /pubmed/29756006 http://dx.doi.org/10.1007/s41048-018-0054-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Opinion
Kang, Jian-Sheng
Theoretical model and characteristics of mitochondrial thermogenesis
title Theoretical model and characteristics of mitochondrial thermogenesis
title_full Theoretical model and characteristics of mitochondrial thermogenesis
title_fullStr Theoretical model and characteristics of mitochondrial thermogenesis
title_full_unstemmed Theoretical model and characteristics of mitochondrial thermogenesis
title_short Theoretical model and characteristics of mitochondrial thermogenesis
title_sort theoretical model and characteristics of mitochondrial thermogenesis
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937889/
https://www.ncbi.nlm.nih.gov/pubmed/29756006
http://dx.doi.org/10.1007/s41048-018-0054-2
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