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Ag85A-specific CD4(+) T cell lines derived after boosting BCG-vaccinated cattle with Ad5-85A possess both mycobacterial growth inhibition and anti-inflammatory properties

There is a need to improve the efficacy of the BCG vaccine against human and bovine tuberculosis. Previous data showed that boosting bacilli Calmette-Guerin (BCG)-vaccinated cattle with a recombinant attenuated human type 5 adenovirally vectored subunit vaccine (Ad5-85A) increased BCG protection and...

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Detalles Bibliográficos
Autores principales:	Metcalfe, Hannah J., Biffar, Lucia, Steinbach, Sabine, Guzman, Efrain, Connelley, Tim, Morrison, Ivan, Vordermeier, H. Martin, Villarreal-Ramos, Bernardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937909/ https://www.ncbi.nlm.nih.gov/pubmed/29655632 http://dx.doi.org/10.1016/j.vaccine.2018.03.068

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