Cargando…

Comprehensive assessment of measurement uncertainty in (13)C-based metabolic flux experiments

In the field of metabolic engineering (13)C-based metabolic flux analysis experiments have proven successful in indicating points of action. As every step of this approach is affected by an inherent error, the aim of the present work is the comprehensive evaluation of factors contributing to the unc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mairinger, Teresa, Wegscheider, Wolfhard, Peña, David Alejandro, Steiger, Matthias G., Koellensperger, Gunda, Zanghellini, Jürgen, Hann, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937919/ https://www.ncbi.nlm.nih.gov/pubmed/29654338 http://dx.doi.org/10.1007/s00216-018-1017-7

Ejemplares similares

Implementation of data-dependent isotopologue fragmentation in (13)C-based metabolic flux analysis
por: Mairinger, Teresa, et al.
Publicado: (2017)

Increasing pentose phosphate pathway flux enhances recombinant protein production in Pichia pastoris
por: Nocon, Justyna, et al.
Publicado: (2016)

Flux tope analysis: studying the coordination of reaction directions in metabolic networks
por: Gerstl, Matthias P, et al.
Publicado: (2019)

Elemental labelling combined with liquid chromatography inductively coupled plasma mass spectrometry for quantification of biomolecules: A review
por: Kretschy, Daniela, et al.
Publicado: (2012)

Complementing reversed-phase selectivity with porous graphitized carbon to increase the metabolome coverage in an on-line two-dimensional LC-MS setup for metabolomics
por: Ortmayr, Karin, et al.
Publicado: (2015)

From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints
por: Klamt, Steffen, et al.
Publicado: (2017)

Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer
por: Herrmann, Helena A., et al.
Publicado: (2021)

Which sets of elementary flux modes form thermodynamically feasible flux distributions?
por: Gerstl, Matthias P., et al.
Publicado: (2016)

Metabolomics integrated elementary flux mode analysis in large metabolic networks
por: Gerstl, Matthias P., et al.
Publicado: (2015)

Chemometrics in Europe: Selected Results
por: Wegscheider, Wolfhard
Publicado: (1988)

Yeast-based reference materials for quantitative metabolomics
por: Wasito, Hendri, et al.
Publicado: (2021)

EFMlrs: a Python package for elementary flux mode enumeration via lexicographic reverse search
por: Buchner, Bianca A, et al.
Publicado: (2021)

Critical assessment of different methods for quantitative measurement of metallodrug-protein associations
por: Galvez, Luis, et al.
Publicado: (2018)

Modeling and measuring intracellular fluxes of secreted recombinant protein in Pichia pastoris with a novel (34)S labeling procedure
por: Pfeffer, Martin, et al.
Publicado: (2011)

Homologue series detection and management in LC-MS data with homologueDiscoverer
por: Mildau, Kevin, et al.
Publicado: (2022)

BayFlux: A Bayesian method to quantify metabolic Fluxes and their uncertainty at the genome scale
por: Backman, Tyler W. H., et al.
Publicado: (2023)

Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production
por: Nocon, Justyna, et al.
Publicado: (2014)

Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs
por: Jungreuthmayer, Christian, et al.
Publicado: (2015)

A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
por: Ata, Özge, et al.
Publicado: (2018)

Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
por: Delic, Marizela, et al.
Publicado: (2014)

Robustifying Experimental Tracer Design for(13)C-Metabolic Flux Analysis
por: Beyß, Martin, et al.
Publicado: (2021)

Treatment of flux shape uncertainties in unfolded, flux-averaged neutrino cross-section measurements
por: Koch, Lukas, et al.
Publicado: (2020)

Selective and Accurate Quantification of N-Acetylglucosamine in Biotechnological Cell Samples via GC–MS/MS and GC–TOFMS
por: Mairinger, Teresa, et al.
Publicado: (2020)

Improving Accuracy in Graphite Furnace Atomic Absorption Spectrometry Through Peak Shape Monitoring
por: Michaelis, Markus, et al.
Publicado: (1988)

Exact quantification of cellular robustness in genome-scale metabolic networks
por: Gerstl, Matthias P., et al.
Publicado: (2016)

Environmental flexibility does not explain metabolic robustness
por: Libiseller-Egger, Julian, et al.
Publicado: (2020)

p(13)CMFA: Parsimonious (13)C metabolic flux analysis
por: Foguet, Carles, et al.
Publicado: (2019)

OpenFLUX: efficient modelling software for (13)C-based metabolic flux analysis
por: Quek, Lake-Ee, et al.
Publicado: (2009)

Comparison between elementary flux modes analysis and 13C-metabolic fluxes measured in bacterial and plant cells
por: Beurton-Aimar, Marie, et al.
Publicado: (2011)

A Comprehensive Metabolic Profile of Cultured Astrocytes Using Isotopic Transient Metabolic Flux Analysis and (13)C-Labeled Glucose
por: Amaral, Ana I., et al.
Publicado: (2011)

Inclusion of maintenance energy improves the intracellular flux predictions of CHO
por: Széliová, Diana, et al.
Publicado: (2021)

FiatFlux – a software for metabolic flux analysis from (13)C-glucose experiments
por: Zamboni, Nicola, et al.
Publicado: (2005)

The Design of FluxML: A Universal Modeling Language for (13)C Metabolic Flux Analysis
por: Beyß, Martin, et al.
Publicado: (2019)

Chasing the Major Sphingolipids on Earth: Automated Annotation of Plant Glycosyl Inositol Phospho Ceramides by Glycolipidomics
por: Panzenboeck, Lisa, et al.
Publicado: (2020)

Metabolic networks in motion: (13)C-based flux analysis
por: Sauer, Uwe
Publicado: (2006)

Design of Optimally Constructed Metabolic Networks of Minimal Functionality
por: Ruckerbauer, David E., et al.
Publicado: (2014)

Optimal knockout strategies in genome-scale metabolic networks using particle swarm optimization
por: Nair, Govind, et al.
Publicado: (2017)

Corrigendum: The Design of FluxML: A Universal Modeling Language for (13)C Metabolic Flux Analysis
por: Beyß, Martin, et al.
Publicado: (2019)

Proposing a validation scheme for (13)C metabolite tracer studies in high-resolution mass spectrometry
por: Schwaiger-Haber, Michaela, et al.
Publicado: (2019)

Probabilistic quotient’s work and pharmacokinetics’ contribution: countering size effect in metabolic time series measurements
por: Gotsmy, Mathias, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i30hppag22rf5ik5gkmm6ag45t