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Translation is actively regulated during effector CD8(+) T cell differentiation

Translation is a critical process in protein synthesis, but translational regulation in antigen-specific T cells in vivo has not been well defined. Here we have characterized the translatome of virus-specific effector CD8(+) T cells during acute LCMV infection of mice. Antigen-specific T cells exert...

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Detalles Bibliográficos
Autores principales: Araki, Koichi, Morita, Masahiro, Bederman, Annelise G., Konieczny, Bogumila T, Kissick, Haydn T., Sonenberg, Nahum, Ahmed, Rafi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937989/
https://www.ncbi.nlm.nih.gov/pubmed/28714979
http://dx.doi.org/10.1038/ni.3795