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Role of phospholipase D in the lifespan of Caenorhabditis elegans

We have previously shown that phospholipase D (PLD) downregulation accelerates cellular senescence, which is widely believed to play an important role in aging, by stimulating reactive oxygen species (ROS) accumulation in human cells. In this study, we examined the role of PLD in aging using the nem...

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Detalles Bibliográficos
Autores principales: Park, Jeong-Hwan, Park, Jeong-Woo, Lee, Ju-Hyeon, Kim, Dong-Yun, Hahm, Jeong-Hoon, Bae, Young-Seuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938010/
https://www.ncbi.nlm.nih.gov/pubmed/29622768
http://dx.doi.org/10.1038/s12276-017-0015-8