Cargando…

Small-conductance Ca(2+)-activated K(+) channels: insights into their roles in cardiovascular disease

Life-threatening malignant arrhythmias in pathophysiological conditions can increase the mortality and morbidity of patients with cardiovascular diseases. Cardiac electrical activity depends on the coordinated propagation of excitatory stimuli and the generation of action potentials in cardiomyocyte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Mingxia, Zhu, Yanrong, Yin, Xiaorong, Zhang, Dai-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938042/ https://www.ncbi.nlm.nih.gov/pubmed/29651007 http://dx.doi.org/10.1038/s12276-018-0043-z

Ejemplares similares

Gating of Recombinant Small-Conductance Ca-activated K(+) Channels by Calcium
por: Hirschberg, Birgit, et al.
Publicado: (1998)

Editorial The Role of Ca(2+)-activated K(+) Channels of Intermediate Conductance in Glioblastoma Malignancy
por: Catacuzzeno, Luigi, et al.
Publicado: (2018)

Evidence for a Deep Pore Activation Gate in Small Conductance Ca(2+)-activated K(+) Channels
por: Bruening-Wright, Andrew, et al.
Publicado: (2007)

Cancer-Associated Intermediate Conductance Ca(2+)-Activated K(+) Channel K(Ca)3.1
por: Mohr, Corinna J., et al.
Publicado: (2019)

Impact of arrhythmogenic calmodulin variants on small conductance Ca(2+)‐activated K(+) (SK3) channels
por: Saljic, Arnela, et al.
Publicado: (2019)

Allosteric Gating of a Large Conductance Ca-activated K(+) Channel
por: Cox, D.H., et al.
Publicado: (1997)

Membrane-delimited Inhibition of Maxi-K Channel Activity by the Intermediate Conductance Ca(2+)-activated K Channel
por: Thompson, Jill, et al.
Publicado: (2006)

Knockdown of the small conductance Ca(2+)‐activated K(+) channels is potently cytotoxic in breast cancer cell lines
por: Abdulkareem, Zana Azeez, et al.
Publicado: (2015)

Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca(2+)-Activated K(+) Channels in Pigs
por: Diness, Jonas Goldin, et al.
Publicado: (2017)

Mechanism of charybdotoxin block of the high-conductance, Ca2+- activated K+ channel
Publicado: (1988)

Selectivity filter gating in large-conductance Ca(2+)-activated K(+) channels
por: Thompson, Jill, et al.
Publicado: (2012)

Small-Conductance Ca(2+)-Activated K(+) Channel 2 in the Dorsal Horn of Spinal Cord Participates in Visceral Hypersensitivity in Rats
por: Song, Yu, et al.
Publicado: (2018)

Intrinsic Voltage Dependence and Ca(2+) Regulation of mslo Large Conductance Ca-activated K(+) Channels
por: Cui, J., et al.
Publicado: (1997)

Inhibition of Small-Conductance, Ca(2+)-Activated K(+) Current by Ondansetron
por: Guo, Shuai, et al.
Publicado: (2021)

Ca(2+)/Calmodulin-Dependent Protein Kinase II (CaMKII) Increases Small-Conductance Ca(2+)-Activated K(+) Current in Patients with Chronic Atrial Fibrillation
por: Fan, Xuehui, et al.
Publicado: (2018)

Small conductance Ca(2+)-activated K(+) channels induce the firing pause periods during the activation of Drosophila nociceptive neurons
por: Onodera, Koun, et al.
Publicado: (2017)

Up-Regulatory Effects of Curcumin on Large Conductance Ca(2+)-Activated K(+) Channels
por: Chen, Qijing, et al.
Publicado: (2015)

Structure, Gating and Basic Functions of the Ca(2+)-activated K Channel of Intermediate Conductance
por: Sforna, Luigi, et al.
Publicado: (2018)

Coronary Large Conductance Ca(2+)-Activated K(+) Channel Dysfunction in Diabetes Mellitus
por: Lu, Tong, et al.
Publicado: (2021)

The Natural Flavone Acacetin Blocks Small Conductance Ca(2+)-Activated K(+) Channels Stably Expressed in HEK 293 Cells
por: Chen, Kui-Hao, et al.
Publicado: (2017)

Role of the β1 Subunit in Large-Conductance Ca(2+)-Activated K(+) Channel Gating Energetics: Mechanisms of Enhanced Ca(2+) Sensitivity
por: Cox, D.H., et al.
Publicado: (2000)

Redox Regulation of Large Conductance Ca(2+)-activated K(+) Channels in Smooth Muscle Cells
por: Wang, Zhao-Wen, et al.
Publicado: (1997)

Coupling of voltage-dependent gating and Ba++ block in the high- conductance, Ca++-activated K+ channel
Publicado: (1987)

Multi-ion occupancy alters gating in high-conductance, Ca(2+)-activated K+ channels
Publicado: (1991)

Intermediate Conductance Ca(2+)-Activated K(+) Channels Modulate Human Placental Trophoblast Syncytialization
por: Díaz, Paula, et al.
Publicado: (2014)

Characterization and Chemical Synthesis of Cm39 (α-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K(+) Channel K(V)1.2 and Small- and Intermediate-Conductance Ca(2+)-Activated K(+) Channels K(Ca)2.2 and K(Ca)3.1
por: Naseem, Muhammad Umair, et al.
Publicado: (2023)

Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca(2+)-Activated K(+) Channels (BK(Ca))
por: Tseng, Hisa Hui Ling, et al.
Publicado: (2016)

Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca(2+)-Activated K(+) Channels, KCa3.1 and KCa2.3
por: Oliván-Viguera, Aida, et al.
Publicado: (2013)

The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca(2+)-activated K(+) channels
por: Bondarenko, Alexander I., et al.
Publicado: (2011)

Rectifying conductance substates in a large conductance Ca(2+)- activated K+ channel: evidence for a fluctuating barrier mechanism
Publicado: (1996)

Midazolam’s Effects on Delayed-Rectifier K(+) Current and Intermediate-Conductance Ca(2+)-Activated K(+) Channel in Jurkat T-lymphocytes
por: Foo, Ning-Ping, et al.
Publicado: (2021)

Functional Regulation of K(ATP) Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases
por: Wang, Zhicheng, et al.
Publicado: (2022)

Separation of Gating Properties from Permeation and Block in mslo Large Conductance Ca-activated K(+) Channels
por: Cox, D.H., et al.
Publicado: (1997)

Reconciling the discrepancies on the involvement of large-conductance Ca(2+)-activated K channels in glioblastoma cell migration
por: Catacuzzeno, Luigi, et al.
Publicado: (2015)

Downregulation of L‐Type Voltage‐Gated Ca(2+), Voltage‐Gated K(+), and Large‐Conductance Ca(2+)‐Activated K(+) Channels in Vascular Myocytes From Salt‐Loading Offspring Rats Exposed to Prenatal Hypoxia
por: Liu, Bailin, et al.
Publicado: (2018)

Intermediate-Conductance-Ca2-Activated K Channel Intermediate-Conductance Calcium-Activated Potassium Channel (IKCa1) is Upregulated and Promotes Cell Proliferation in Cervical Cancer
por: Liu, Ling, et al.
Publicado: (2017)

Charybdotoxin selectively blocks small Ca-activated K channels in Aplysia neurons
Publicado: (1987)

The Activation Effect of Hainantoxin-I, a Peptide Toxin from the Chinese Spider, Ornithoctonus hainana, on Intermediate-Conductance Ca(2+)-Activated K(+) Channels
por: Huang, Pengfei, et al.
Publicado: (2014)

Structure of the Gating Ring from the Human High-conductance Ca(2+)-gated K(+) Channel
por: Wu, Yunkun, et al.
Publicado: (2010)

Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of K(Ca)2.x and K(Ca)3.1 Channels
por: Kloza, Monika, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3fchuilql4frb6i21idgd57qu4