MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways

Pulmonary vascular remodeling due to excessive proliferation and resistance to apoptosis of pulmonary artery smooth muscle cells (PASMCs) is the hallmark feature of pulmonary arterial hypertension (PAH). Recent evidence suggests that miR-125a-5p plays a role in a rat model of monocrotaline-induced P...

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Detalles Bibliográficos
Autores principales: Cai, Zongye, Li, Jian, Zhuang, Qi, Zhang, Xueming, Yuan, Ancai, Shen, Lan, Kang, Kang, Qu, Bo, Tang, Yuanjia, Pu, Jun, Gou, Deming, Shen, Jieyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938047/
https://www.ncbi.nlm.nih.gov/pubmed/29700287
http://dx.doi.org/10.1038/s12276-018-0068-3

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