TAK-733 inhibits inflammatory neointimal formation by suppressing proliferation, migration, and inflammation in vitro and in vivo

As a potent and selective allosteric inhibitor of MEK, TAK-733 has been shown to exert anti-cancer effects for a wide range of cancers both in vitro and in vivo. However, its effects on inhibiting growth have never been investigated in the cardiovascular system, where regulation of abnormal vascular...

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Detalles Bibliográficos
Autores principales: Park, Jun-Hee, Kim, Sang Woo, Cha, Min-Ji, Yoon, Nara, Lee, Chang Youn, Lee, Jiyun, Seo, Hyang-Hee, Shin, Sunhye, Choi, Jung-Won, Lee, Seahyoung, Lim, Soyeon, Hwang, Ki-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938062/
https://www.ncbi.nlm.nih.gov/pubmed/29674718
http://dx.doi.org/10.1038/s12276-018-0052-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938062/
https://www.ncbi.nlm.nih.gov/pubmed/29674718
http://dx.doi.org/10.1038/s12276-018-0052-y

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